Phosphatidylserine (PS) is one of the phospholipids. Phosphatidylserine consists of three parts: two long chains of fatty acids, a glycerol backbone and a phospholipid headgroup.
PS is present in the biofilm of all animals, higher plants and microorganisms and is one of the important components of cell membrane phospholipids. It accounts for 10%-20% of all phospholipids in the mammalian brain and has an important role in regulating many cellular metabolic processes.
As one of the main neurological components of the brain, PS can nourish and activate the activity of various enzymes in the brain, slow down the process of neurotransmitter reduction, help repair and renew damaged cells in the brain and remove harmful substances. In particular, it plays an important role in regulating the brain's memory and emotional stability, and it significantly reduces the level of stress hormones in the body of people who work under stress, reducing stress and relieving brain fatigue.
Therefore, identifying the levels of PS can provide new insights into the pathogenesis of the disease. Analysis of PS levels against nutritional supplements can help in quality control.
Fig 1. Intracellular transport of PS (Kim HY et al., 2014)
Creative Proteomics provides you with efficient and accurate phosphatidylserine qualitative and quantitative detection services through advanced chromatography and mass spectrometry platforms.
Absolute quantification: Use external standard method to quantify, and use internal standard for correction, qualitative and quantitative is more accurate.
High sensitivity: We use liquid chromatography coupled with triple quadrupole mass spectrometers for phosphatidylserine analysis service (Triple Quad™ 6500 LC-MS/MS System).
Fig 2. The workflow of phosphatidylserine analysis service
We routinely cover a rich variety of sample types, including tissue, serum, cells, cell medium, food products, et al. for our customer.
Extraction of lipids should be performed right after sample collection steps, otherwise, samples should be stored at -80°C, and shipped with dry ice.
After sample collection, you can either perform sample pretreatment, or contact us for specific sample pretreatment service.
If you have any questions about our phosphatidylserine detection service, please contact us.