The lipids found in microorganisms can be substantially different from those in eukaryotic systems, but they are equally important for maintaining the structure of the microbiology and providing protection from the surrounding environment. Compared with mammals lipidomics research, microorganisms lipidomics research has the following advantages, (1) The lipidomics are relatively simple (The types of fatty acids in microbial cells are less than those in mammals, and there are no polyunsaturated fatty acids); (2) The microbial culture time is short and the culture process is relatively simple; (3) A large number of mutants are produced by gene knockout technology, which can be further analyzed by studying the effect of the gene at the molecular and cellular levels.
In recent years, the research of lipomics in the field of microbiology has been developed rapidly, including the study of microbial phenotype, the study of microbial infectivity and the mechanism of microbial drug resistance. Therefore, the research on lipids and their interaction molecules has become the research focus in the field of microbiology. Creative Proteomics provides reliable, rapid and cost-effective microorganisms lipidomics based on LC-MS or shot-gun methods for biomedical research institutions, biotechnology and pharmaceutical companies.
Infectious diseases are a continuous burden on global health. AIDS, Malaria and Tuberculosis are the top three infectious diseases by scale of mortality. As a result it is becoming increasingly evident that lipids play important roles at various stages of host–pathogen interactions. They act in first line recognition and host cell signaling during pathogen docking, invasion and intracellular trafficking. Lipid metabolism is a housekeeping function in energy homeostasis and biomembrane synthesis during pathogen replication and persistence. With decades of operational experience and technology platform, Creative Proteomics provides reliable, rapid, and cost-effective microorganisms lipidomics services based on LC-MS or shot-gun methods for host–pathogen interactions research.
Learn MoreThe severity of the ongoing antibiotic resistance crisis is leading to novel and creative approaches to characterize and classify bacteria. While the field has largely been driven by genomics and transcriptomics, there is growing use of mass spectrometry–based lipidomics, towards the study of microbial systems. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) platforms has been established for the identification of microbial species. Recent works on bacterial lipid analysis by MS have demonstrated that lipidomic signatures of microorganisms may be equally or more powerful than those based on proteomics. Creative Proteomics provides reliable, rapid, and cost-effective microorganisms lipidomics services based on MALDI-TOF methods for antibiotic resistance research.
Learn MoreWe are dedicated to providing cutting-edge mass spectrometry (MS)-based lipidomics services for research institutions and biotechnology and pharmaceutical companies.
Learn MoreLipid analysis fuels research and progress in biotech and pharma, disease research, food & nutrition, agriculture.
Numerous human pathologies involve changes in lipid metabolism. Likewise, a growing number of drugs are being developed that directly or indirectly affect lipid metabolic pathways. Instead of classical and cumbrous radiochemical analyses, lipid profiling by mass spectrometry (MS)-based lipidomics holds great potential as companion diagnostic in several steps along the drug development process. Creative Proteomics provides a perfect lipidomics platform for drug research.
Learn MoreThe MS analysis of lipids in biological samples has provided abundant information for clinical interpretations of many diseases. With extensive experience and state-of-the-art technologies, Creative Proteomics provides comprehensive lipidomics services from lipid extraction, lipid detection and data analysis for disease research.
Learn MoreThe feasibility of MS-based lipidomics approaches in the field of foodomics has been demonstrated with their recent applications in food traceability, quality, safety, as well as revealing the health benefits of dietary lipids. With decades of operational experience and technology platform, Creative Proteomics provides reliable, rapid, and cost-effective untargeted lipidomics and targeted lipidomics services based on GC/LC-MS and shot-gun methods for Food & Nutrition research.
Learn MoreThe identification and quantification of lipids from plant tissues have become commonplace and many researchers now incorporate lipidomics approaches into their experimental studies. With decades of operational experience and technology platform, Creative Proteomics provides reliable, rapid, and cost-effective plant untargeted lipidomics and targeted lipidomics services.
Learn MoreThe versatility of lipidomic applications has been increasingly recognized in environmental toxicology in recent years. The unmatched diversity and ubiquitous nature of lipids makes them exceptional candidates in the discovery of sensitive biomarkers for various diseases in animals and humans. Lipidomics as a tool to examine the effects of environmental stress using in vitro and in vivo models. Creative Proteomics provides reliable, rapid, and cost-effective untargeted lipidomics and targeted lipidomics services based on GC/LC-MS and shot-gun methods for environmental toxicology research.
Learn MoreThe lipids found in microorganisms can be substantially different from those in eukaryotic systems, but they are equally important for maintaining the structure of the microbiology and providing protection from the surrounding environment. In recent years, the research of lipomics in the field of microbiology has been developed rapidly, including the study of microbial phenotype, the study of microbial infectivity and the mechanism of microbial drug resistance. Creative Proteomics provides reliable, rapid and cost-effective microorganisms lipidomics based on LC-MS or shot-gun methods for biomedical research institutions, biotechnology and pharmaceutical companies.
Learn More