Glycerophospholipids are important structural and functional components of biological membranes and constituents of serum lipoproteins and the pulmonary surfactant. In addition, glycerophospholipids act as precursors of lipid mediators such as platelet-activating factor and eicosanoids.
Cellular membranes contains a distinct composition of various glycerophospholipids such as phosphatidic acid (PA), phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS), phosphatidylglycerol (PG), phosphatidylinositol (PI), cardiolipin (CL), lysophosphatidic acid (LPA) and lysobisphosphatidic acid (also known as bis(monoacylglycerol) hydrogen phosphate - BMP).
Creative Proteomics provides rapid and cost-effective glycerophospholipids analysis based on a highly stable, repeatable, and highly sensitive system for separation, characterization, identification, and quantitative analysis.
Creative Proteomics use liquid or gas chromatography coupled with triple quadrupole mass spectrometers for glycerophospholipids detection.
Fig1. The workflow of glycerophospholipids targeted lipidomics
We can accept a variety of sample types, including cells, tissues, blood, plasma, skin, urine, feces, plants, microorganisms, et al.
Extraction of lipids should be performed right after sample collection steps, otherwise, samples should be stored at -80°C, and shipped with dry ice. After sample collection, you can either perform sample pretreatment, or contact us for specific sample pretreatment service.
If you have any questions about our glycerophosphocholines analysis services, please contact us.