Lipids have many key biological functions in cancer. Lipid metabolism and metabolites are characteristically altered in different physiological and pathological processes. Lipidomics is an emerging discipline of metabolomics for the systematic analysis of lipids and the molecules interacting with them in organisms, tissues or cells. With the development of new analytical techniques, especially the application and development of mass spectrometry, the determination of lipids can be performed rapidly, accurately and with high throughput. Abnormalities in lipid metabolism are closely related to tumorigenesis and development. Analysis of lipid metabolism changes associated with cancer cells and tumor tissues can provide data support for basic and translational research.
Lipidomics technology can reveal the lipid changes and relatively abnormal metabolic pathways associated with cancer, and has a wide range of applications in the identification of lipid biomarkers of cancer, early diagnosis of cancer, and discovery of anti-cancer drug targets.
Creative Proteomics offers customized lipidomics solutions for qualitative and quantitative assessment of lipids in body fluids, tissues or cells, accelerated cancer pathogenesis research and cancer biomarker screening.
Based on liquid chromatography–mass spectrometry (LC-MS) technology, the experimental process of lipidomics research mainly includes sample collection, lipid extraction, LC-MS/MS detection and data analysis, etc.
Lipidomics Analysis Process (Wang et al., 2021)
If you have any questions about our lipidomics services for cancer research, please contact us. Let us know what you need and we will accommodate you. We look forward to working with you in the future.
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