Lipidomics for Cancer Biomarkers Discovery

The prevention, diagnosis and targeted therapies of cancer are important in cancer controlling and treatment. The present challenge about cancer biomarker still remains in identifying the special biomarkers for predicting cancer risk and assessing patient's response during anticancer treatment.

Lipids play critical functions in cellular survival, proliferation, interaction and death, since they are involved in chemical-energy storage, cellular signaling, cell membranes, and cell–cell interactions.
These cellular processes are strongly related to carcinogenesis pathways, particularly to transformation, progression, and metastasis, suggesting the bioactive lipids are mediators of a number of oncogenic processes.

Therefore, bioactive lipids play an important role in many biological process, in particular their composition is altered in many neoplastic diseases. Lipidomics methods are widely used in identification and validation of tumour-specific biomarkers, which are required more sensitive and specific to tumour severity, duration, subtype, and response to therapy. Creative Proteomics provides reliable, rapid and cost-effective lipidomics services for cancer biomarkers discovery.

Featured services

Mammals Untargeted Lipidomics
Fatty Acyls Targeted Lipidomics
Glycerolipids Targeted Lipidomics

Sterol Lipids Targeted Lipidomics
Glycerophospholipids Targeted Lipidomics
Sphingolipids Targeted Lipidomics

Creative Proteomics also provide some other services involved in the above steps

Primary Cell Separation

Mitochondrial Isolation

Our platform for cancer biomarkers discovery

Liquid chromatography hyphenated to high resolution /high accuracy mass spectrometry for untargeted lipidomics
Shotgun throughput lipidomics analysis

Cancer Biomarkers Discovery

Creative Proteomics designs experimental programs according to customer needs and choose different technical methods to improve detection efficiency and ensure the accuracy and repeatability of experimental results.

PLATFORM

Advantages

Our project is a very complex study that requires a high degree of sensitivity and accuracy. Creative Proteomics has molecular biologists, mass spectrometry specialists, bioinformatics experts, and lipidomics data scientists. We are well-prepared and positioned to foster collaboration in the fast-developing field of lipidomics.
A detailed report will be provided at the end of the whole project, including the experiment procedure, MS/MS instrument parameter, raw data and data reports with figures, ready to be published.

How we work in 7 easy steps

Inquiry

If you have any questions about our lipidomics services for cancer biomarkers discovery, please contact us. Our customer service representatives are available 24hr a day!

Reference:

Perrotti F., et al. Advances in lipidomics for cancer biomarkers discovery[J]. International journal of molecular sciences. 2016, 17(12): 1992.

* Our services can only be used for research purposes and Not for clinical use.

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