Food, like medicine, can prevent and cure diseases, which is open to new interpretation nowadays. Specific types of food or diet are deemed to have the impact of affecting health and disease.
Lipids are metabolites of an individual's diet and metabolic pathways. Accurate measurement of all lipids within a single biological fluid, tissue, or cell type through MS‐based lipidomics can effectively establish the association between diet and health.
Lipid homeostasis plays an important role in maintaining health, while disordered lipid metabolism may lead to a variety of diseases, such as inflammation, metabolic syndrome (MetS), CVD, neurodegenerative diseases, and cancer. In recent years, many studies have found that diet has great potential in promoting health and delaying the development of these diseases via changes in lipid metabolism.
|Inflammation||Dietary supplementation with marine ω-3 PUFAs can effectively reduce proinflammatory ω-3 and ω-6 lipid mediators.|
|Metabolic syndrome||It was found that a healthy Nordic diet affected plasma lipidomic profile of MetS subjects, with an increase in antioxidative plasmalogens and a decrease in insulin resistance-inducing CerT.|
|Cardiovascular disease||The levels of fatty acids and GLs in the heart of mice on atherogenic diet varied depending on the degree of unsaturation, with higher percentage of palmitic acid (16:0), stearic acid (18:0), and DAG (36:0) in mice on an atherogenic diet than those on a normal diet.|
Creative Proteomics provides comprehensive food untargeted lipidomics services from lipid extraction, lipid detection and data analysis for biomedical research institutions, biotechnology and pharmaceutical companies.
We routinely cover a rich variety of sample types, including cells, conditioned medium, subcellular compartments, exsome, tissue, blood, plasma, breast milk, skin, urine, fecal for our customer. Still, our services require only minimal sample amounts per analysis.
Fig1. The protocol workflow of food untargeted lipidomics in nutrition and human health. (Creative Proteomics)
If you have any questions about our food untargeted lipidomics services, welcome to contact us.